Osmolarity & Solution Tonicity Calculator
Calculate osmotic pressure and solution tonicity for clinical and research applications
Free online osmolarity calculator for calculating osmolarity, osmolality, and solution tonicity. Determine whether IV solutions are isotonic, hypertonic, or hypotonic. Essential for clinical medicine, pharmacy, dialysis, and biomedical research applications with professional accuracy.
Common values: NaCl = 2, CaCl₂ = 3, Glucose = 1
Formula:
Osmolarity (Osm/L) = Molarity (M) × Dissociation Factor (i)
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Professional Osmolarity Calculator Features
Comprehensive osmolarity calculator with advanced features designed for clinicians, pharmacists, laboratory technicians, and research scientists
Professional osmolarity calculations in seconds
Calculate solution osmolarity using van 't Hoff equation with detailed clinical implications for IV fluid selection and quality verification
Select solute type and enter concentration (M, mM, g/L, %)
Input or use built-in van 't Hoff factors for dissociating solutes
Add multiple solutes for complex IV solutions or formulations
Get instant osmolarity in mOsm/L with osmolality in mOsm/kg
See automatic tonicity classification (isotonic/hypertonic/hypotonic)
Compare to physiological reference values for clinical appropriateness
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From solution composition to clinical tonicity in seconds
See how our calculator provides instant, accurate osmolarity calculations with complete tonicity analysis for all your clinical and research needs
What Clinical & Research Professionals Say
Feedback from physicians, pharmacists, clinical laboratory directors, nurses, and biomedical researchers
"Essential tool for IV fluid verification! We use this daily to confirm osmolarity of compounded solutions. Catches potential errors before administration. Meets hospital pharmacy standards."
Dr. Michael Torres
Clinical Pharmacist
"Perfect for teaching nursing students about IV tonicity! The clinical classification and safety warnings help new nurses understand why solution selection matters. Highly recommended."
Sarah Mitchell
ICU Nurse Educator
"Invaluable for dialysate osmolarity calculations! Ensures our hemodialysis solutions are properly formulated. The multiple solute support is particularly helpful for complex prescriptions."
Dr. James Anderson
Nephrologist
"Excellent for osmotic cell studies! The colligative properties calculations help us design proper experimental conditions. Precise and reliable for published research."
Dr. Elena Rossi
Biomedical Research Scientist
"We standardized all our solution osmolarity verification around this calculator. Reliable, fast, and meets clinical laboratory standards. Great support for quality assurance."
Dr. Robert Chen
Laboratory Director
Frequently Asked Questions About Osmolarity & Tonicity
Common questions about osmolarity calculations, solution tonicity, and clinical applications
Ready to master osmolarity calculations?
Use our professional osmolarity calculator for accurate clinical tonicity determination with comprehensive solution analysis and safety guidelines